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El Sharkwy IA, Abd El Aziz WM
By also activating GIP (glucose-dependent insulinotropic polypeptide) receptors, tirzepatide enhances insulin sensitivity through a pathway that is still being fully characterized by researchers
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Notable conformational differences were observed in the positions of peptide C-terminal half and the surrounding extracellular loop 1 (ECL1) and extracellular domain (ECD), indicative of GIPR-associated ligand specificity
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