Regarding Tamoxifen, we assume that it interacts with estrogen receptors, resulting in detachment from the last molecules of HSP70, which subsequently acts as a cytoprotector
But chronic stress, poor diet, infections, medications, and inflammatory conditions can damage the intestinal lining, leading to issues like leaky gut, IBS, inflammatory bowel disease (IBD), and food sensitivities
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Edited by Professor Boris Zhivotovsky Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made
Nature 616 , 598605 (2023)
This was the first major setback, suggesting preclinical results might not translate to human disease