Publisher | Google Scholor Reiss AB, Gulkarov S, Lau R, Klek SP, Srivastava A, et al
It's not as vulnerable to being broken down in the stomach
The FDA explains that GLP-1 receptor agonists mimic the effects of a natural hormone released by the intestine, help lower blood sugar after eating, and act on brain regions involved in appetite and food intake
In 1987, Flier co-founded a biotech start-up that pursued GLP-1 as a potential treatment for diabetes, not long after it had first been identified by researchers whod also found that the hormone enhanced insulin secretion in the presence of glucose
Lets compare the approaches
Although at lower thresholds, the glycan chain density extends out significantly (~20 ) (Supplementary Fig