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Turtoi, A

doi: 10.1159/000118012

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The accelerated healing in burns of treated mice includes the activity of the pentadecapeptide BPC 157 (Figure 1), given locally (as a cream) or systemically (ip), on the inflammatory cells, edema, reticulin, collagen, necrosis, blood vessel formation, number of preserved follicles, re-epithelization, tensile breaking strength, and water content in burned skin

BPC-157 vs LL-37 BPC-157 and LL-37 are both studied for wound healing but through distinct mechanisms: BPC-157 promotes tissue repair through angiogenesis, fibroblast activation, and nitric oxide modulation