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When the tissue SAM level is sufficient to maintain vital transmethylation reactions, SAM reduces the rate of remethylation of homocysteine into methionine by 5-methylTHF, through an inhibition of MTHFR activity (Fig

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[PMID: 30191288] PubMed record related to this compound for laboratory literature review

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Treatments are customized , and weekly or monthly doses may be recommended based on individual needs