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These quinones combine with DNA to form structures that link with deoxy purine components, and this results in instability in the genome

Rice D, Rodriguez-Restrepo A, Mena G, Cata J, Thall P, Milton D, Correa A, Woodard T, Antonoff M, Hofstetter W, Roth J, Sepesi B, Swisher S, Walsh G, Vaporciyan A, Mehran R

pombe use cysteine rather than -glutamyl cysteine to produce EGT because both fungi appear to lack the glutamine amidotransferase that catalyzes the hydrolysis of the -glutamyl amide bond from S-hercynyl--glutamylcysteine sulfoxide (8, 50)

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