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The findings with DPP-4 inhibitors also differ from the responses reported with SGLT2 inhibitors, which (in two trials) were reported to reduce major adverse cardiovascular events, especially the risk of new-onset heart failure [55, 56]
dulaglutide (1.5 mg weekly) for both non-inferiority and superiority in terms of CV outcomes ( 3.4 Effects on heart failure In addition to their demonstrated CV benefits, GLP-1 RAs have showed promising signals for their potential benefits in HF management
6 Conclusion The impact of poor outcomes in preterm infants has prompted the exploration and optimization of new treatment regimens
The first GLP-1 analog (exenatide) was derived from the surprising source of Gila monster venom and approved in 2005 ( [3] ) ( [4] ), opening a new era of incretin mimetic therapy
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