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8 Driving this change is the cycle of innovation, where complex interventions begin in hospital settings but gradually shift to outpatient and alternative sites due to improvements in technology and payment reform

Activation of GLP-1 receptors also results in nonglycemic effects in a variety of tissues, by acting directly on tissues expressing incretin receptors, as well as through indirect mechanisms regulated by endocrine and neuronal pathways

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Giugliano D, Scappaticcio L, Longo M, Caruso P, Maiorino MI, Bellastella G, et al