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Estimands are defined as targets of estimation based on the trial objectives, providing greater transparency of the effects reported [60]

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This article examines the evidence on concurrent use, potential challenges, and practical guidance for patients and healthcare professionals managing both medications together in UK clinical practice

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Medical Conditions That May Qualify You If your BMI is between 27-29.9, you may still qualify for GLP-1 medications if you have: Type 2 diabetes or prediabetes High blood pressure (hypertension) High cholesterol or dyslipidemia Sleep apnea Cardiovascular disease Metabolic syndrome Insulin resistance These conditions are often interconnected with weight, and GLP-1 for weight loss can help address multiple health concerns simultaneously