A common laboratory dilution is 1 mL of bacteriostatic water per 5mg vial, giving a 5 mg/mL solution
It is important for patients and healthcare providers to monitor for signs of depression or suicidal thoughts
In fact, excessive doses often produce the opposite effect, causing paradoxical insomnia or next-day grogginess
The secondary outcomes were all-cause death, heart failure admission, admission due to any cause, composite major adverse limb events including newly diagnosed peripheral arterial disease, claudication, clinical limb ischemia, limb revascularization or amputation, hypoglycemia, diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS), and infection death
Evidence base GLP-1 medications have extensive randomised controlled trial data demonstrating cardiovascular and renal benefits in addition to glycaemic control
PMID 18991959