When you're eating significantly less which many GLP-1 users do, especially in the early weeks protein is what keeps your body from losing muscle mass along with fat
These results, using either pharmacology or mouse genetics, show that reduction in CNS GIPR signalling can positively impact peripheral tissue metabolism
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These include: Nausea Vomiting Diarrhoea Constipation Decreased appetite (which, whilst therapeutically intended, can occasionally be excessive) Injection-site reactions (such as redness, bruising, or discomfort at the injection site) These effects were generally mild to moderate in severity and most frequently occurred during the dose-escalation phase of treatment, tending to diminish over time
DOI: 10.1021/jm00018a005