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STING is normally part of the cGASSTING innate immune pathway that senses cytosolic DNA and triggers type I interferon responses, helping protect against infection and cellular stress

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Ca(2+) channel blockade reduces cocaine's vasoconstriction and neurotoxicity in the prefrontal cortex

This finding is particularly noteworthy given that some trials extended to 24 weeks of continuous exposure and included participants with obesity-related comorbidities who might be expected to have higher baseline health risks