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Additionally, patients with pre-existing liver conditions should exercise caution with acetaminophen regardless of semaglutide use, as acetaminophen is metabolized by the liver

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In secondary, intention-to-treat analyses, participants were followed from the index date to first SIS event, death, or end of follow-up, and were analysed according to the treatment assigned at baseline, irrespective of actual exposure during follow-up

A Breakthrough Backed by Clinical Evidence The FDAs decision was supported by data from the OASIS 4 Phase 3 clinical trial , which followed 307 adults without diabetes over a 64-week period