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Despite promising preclinical data, clinical trials in humans are extremely limited, and the compound remains largely experimental, with ongoing research required to fully characterize pharmacokinetics, optimal dosing, long-term safety, and potential off-target effects.
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Studies have demonstrated its ability to stimulate collagen and glycosaminoglycan synthesis, attract immune cells to sites of injury, and modulate gene expression related to tissue remodeling
Lack of sterol regulatory element binding factor-1c imposes glial fatty acid utilization leading to peripheral neuropathy
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