It was demonstrated that cysteine S -conjugate -lyase highly expressed in the kidney was responsible for the observed nephrotoxicity (Zhang and Hanigan, 2003
10.1016/J.INTIMP.2003.12.012 68 LeeT
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Kudo, N., Kouno, R
doi:10.1021/bi400651x Go YM, Roede JR, Walkers D, Duong DM, Seyfried NT, Orr M, Liang Y, Pennell KD, Jones DP (2013) Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems