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* N represents the number of participants that finished the treatment in the clinical trial and had a blood draw for the biomarkers under study

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In test-tube studies, alpha-lipoic acid has reduced markers of inflammation, including NF-kB, ICAM-1, VCAM-1, MMP-2, MMP-9, and IL-6 ( May lower heart disease risk factors Heart disease is responsible for one in four deaths in America ( Research from a combination of lab, animal, and human studies has shown that the antioxidant properties of alpha-lipoic acid may lower several heart disease risk factors

For example, both Puritans Pride and Thorne go well above the daily value of vitamin B12 in their respective mens multivitamins

Current Therapeutic Research 1981;30(5):753-764