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Esposito, F., et al

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(1998, Eur J Endocrinol) as a GHS-R1a agonist with GH-release potency comparable to GHRP-6 but without the ACTH, cortisol or prolactin elevation that limits other secretagogues

The DBP model includes six environmental factors (weight, alcohol intake, weekly exercise frequency, triglycerides, parental history of hypertension) and three SNPs (rs5193, rs7305099, rs3889728)

The clinical trial was a key component of this study, as it allowed the researchers to translate their in vitro and ex vivo findings to a real-world scenario, providing more relevant information on how the studied compound behaves in situ