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This ultimately leads to decreased food intake and allows for more calorie loss when paired with increased exercise and activity

The study also found increased expression of PPARalpha and PGC1alpha, transcription factors involved in fat oxidation and mitochondrial biogenesis

This is the body fallback system for maintaining blood glucose when dietary carbohydrates are low

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However, if you are still losing weight steadily and feel good at your current dose, there is no urgent need to increase

[11] People with type 2 diabetes on insulin or sulphonylureas require careful monitoring due to the risk of hypoglycaemia when combining these agents