In this regard, the GIP and GLP-1 agonist, tirzepatide, currently shows promising data derived from phase 2 and 3 clinical trials
Diabetes Care 2015;38:1638-1642
The timing relative to conception and drug-specific safety must be navigated
At the ASGCT 2025 meeting, Fractyl presented data showing low systemic circulating GLP-1 levels with their approach
Two makers of GLP-1s, Eli Lilly and Novo Nordisk, established direct-to-consumer programs to allow patients to buy the medicines without using insurance at prices as low as $149 for starter doses and between $250 and $375 for monthly maintenance doses
To date, dulaglutide, semaglutide, and tirzepatide have been the three predominant GLP-1 therapeutics employed in the treatment of T2DM, and their applications have been broadened to include weight management