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Beyond these three papers, review articles referencing the human peptides discovery in the 1970s continue to shape how researchers frame new hypotheses, particularly around why plasma concentration declines with age and what that means for tissue-repair capacity over time
The intracellular signaling cascades activated during dosing PI3K/Akt/mTOR for synthesis, FoxO suppression for anti-catabolism do not terminate immediately when plasma LR3 clears (Yoshida & Delafontaine, 2020)
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These are unstable atoms that can damage cells and contribute to the aging process
doi:10.3390/molecules20058742 Lushchak VI
The source data for Figs
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