Leukotrienes The term leukotriene was coined because these eicosanoids, first discovered by Samuelsson and colleagues in the white blood cells derived from bone marrow, i.e., the leuk ocytes, have three double bonds in conjugation (though they have four in total), resulting in characteristic absorbance peaks in their UV spectra (at 270, 280 and 290 nm)
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High-fat diet promotes renal injury by inducing oxidative stress and mitochondrial dysfunction
However, as a macromolecular peptide, insulin possesses inherent limitations, such as its large size, poor lipid solubility, and susceptibility to degradation
10.1002/mus.24541 Muscle Nerve 136 LindeR.PengL.DesaiM.FeldmanD
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