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Suppression by exendin-4 of the GABA responses of GCs suggests that exendin-4 weakens inhibitory inputs mediated by GABA, which modulates the receptive field properties of GCs
Accordingly, large clinical trials on the safety and efficacy of these earlier GLP-1 RAs are available
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Results can typically be seen within a few weeks of starting Semaglutide treatment, with progressive improvements over time
From an eating disorder perspective, the root driver of food noise is restrictive, disordered eating, which has many psychological and social underpinnings that also need to be addressed
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