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PMCID: PMC12021486 Steinacker JM, Brkic M, Simsch C, Nething K, Kresz A, Prokopchuk O, Liu Y

References Nauck MA, Meier JJ (2018) Incretin hormones: Their role in health and disease

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Zavegepant exhibited potent inhibition (K i = 23 pM) of CGRP binding to human CGRP receptor expressed in cell membranes and demonstrated potent and full reversal of CGRP-induced dilation of ex vivo human intracranial arteries (EC 50 =880 pM)

Myostatin may thus be deemed crucial in protection from unregulated hypertrophy

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