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theoretical risks include increased hypoglycaemia, unpredictable cardiovascular effects, and compounded uncertainty from two incompletely characterised compounds

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GLP-1 receptor agonists work by mimicking the incretin hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying

Tirzepatide is a dual agonist, affecting both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

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