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Levy AD, Remotti HE, Thompson WM, Sobin LH, Miettinen M

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Life (Basel) 15:1422

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However, the most critical factor remains bioavailability

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Beyond weight outcomes, the Phase 2 obesity trial also reported improvements in several cardiometabolic markers, including: Reductions in waist circumference Improvements in fasting glucose and insulin sensitivity Favourable changes in blood pressure and lipid profiles Phase 3 trials understood to form part of the TRIUMPH programme are now underway, evaluating retatrutide in broader populations including people with type 2 diabetes and cardiovascular disease

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