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Common signs include persistent fatigue (even after a full nights sleep), brain fog, mood swings or irritability, numbness or tingling in the hands or feet, and a weakened immune system
They can also be a great option for individuals who have trouble absorbing B12 from food, which can happen for various reasons
Some patients, particularly those with neurological involvement, may benefit from more frequent dosing (every 2 months rather than 3 months), but this should be medically supervised rather than self-adjusted
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altering its production may affect downstream pathways in ways not yet studied long-term
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