With more severe injury, synapse disruption, axonal injury, excitotoxicity, and cell death also become major effectors
While human clinical trials remain limited, the depth of animal research, consistency of positive findings across multiple study designs, and extensive community experience create a reasonable basis for therapeutic use
No equivalent human data exists specifically for TB-500 in musculoskeletal injuries
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This insight comes from in vitro studies, which means studies done on cells isolated outside of the body (imagine scientists looking under a microscope at a petri dish)
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