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Step 3: Preparation of H-Glu(OtBu)-Gly-Thr(tBu)-Phe-Thr(tBu)-Ser(tBu)-Asp(OtBu)- Val-Ser(tBu)-Ser(tBu)-Tyr(tBu)-Leu-Glu(OtBu)-Gly-Gln(Trt)-Ala-Ala-Lys(Boc)- Glu(OtBu)-Phe-Ile-Ala-Trp(Boc)-Leu-Val-Arg(Pbf)-Gly-Arg(Pbf)-Gly-Resin (3-31) Fmoc-Arg(Pbf)-OH (37.7 gm) was dissolved in DMF (125 ml) at 25-30C

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The maximum dose for immediate-release oral tablets is 2550 mg daily whereas no more than 2000 milligrams daily is advised for extended-release

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Theres no evidence that GLP-1 medications increase seizure risk in most people with epilepsy, and there may be some benefit

Blood glucose levels should be monitored, and the reduction of existing blood glucose-lowering drugs should be considered