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It was previously shown that the GLP-1 receptor can control neuronal function in the rat hippocampus by enhancing GABAA signaling through presynaptic and postsynaptic mechanisms (Korol et al., 2015)

*p-value for interaction between treatment and CV risk quartile

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Semaglutide is a 31-amino acid peptide with a molecular weight of approximately 4,113.58 daltons

Future research will determine whether the industry doubles down on GLP-1 friendly foods or pivots towards natural alternatives but either way, the stakes are high