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High-dose busulfan treatment is correlated with drug-related events such as cataracts and hepatic sinusoidal obstruction syndrome

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Anhedonia can be a challenging symptom to treat, but there are several approaches that individuals, in consultation with mental health professionals, can consider: Medications: Antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and atypical antidepressants, may be prescribed to alleviate anhedonia in cases of depression or other mood disorders

Moreover, several risk factors were linked to the pathophysiology of intestinal dysbiosis, antibiotic usage was shown to both transiently and permanently alter the composition of the gut microbiome (78, 79)

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There is no established human dose, no published human safety data, and no monograph.