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In the first study, published January 29 in JAMA Network Open, a research team from Johns Hopkins University School of Medicine in Baltimore, led by Dr

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Phase 1b/2a results (published in The Lancet, 2025): - In 125 adults with overweight or obesity, the subcutaneous 20 mg dose achieved 22.0% absolute weight loss (23.9% placebo-adjusted)

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Right now, that molecule is Retatrutide