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BPC-157 operates locally as an **ultra-stable cytoprotectant**: it survives gastric milieu, reactivates the VEGF-receptor-2 pathway at the lesion site, modulates the nitric oxide system (NO / eNOS), upregulates growth hormone receptors on tendon fibroblasts (Chang et al
Four proline residues, including an unusual triple-proline sequence, confer resistance to enzymatic degradation
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Chitapanarux, T., Tienboon, P., Pojchamarnwiputh, S., & Leelarungrayub, D
Theranostics 11 , 31963212 (2021)
These cells are essential to maintain blood vessel integrity and blood fluidity [2]
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