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This is the first time-course study to evaluate and compare three clinical GLP-1 analogs in MC4R KO mice
Kowalski, M., et al
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Power calculations suggest that previous studies would have had limited power to detect an effect size similar to that identified in our study (Supplementary Table 23), and also differed in terms of drug type, disease cohort and analytical choices
Women averaged 1.1% body weight loss per week during this phase, compared to 0.95% for men
In comparison, semaglutide resulted in a mean change of 1.86%
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