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If these drugs aren't right for you, whether because you don't have the disease physiology, don't want a lifelong medication, or simply want to try something else first, the lifestyle tools Kushner spent his career refining still matter and can still work, especially for heading off weight gain before it becomes entrenched
B12 increases metabolism which burns fat and results in weight loss
The drop can be more than 30% in some formulas
The GLP-1 landscape changed in 2026
They act as incretin hormone mimetics
At the 2025 ACR Convergence meeting, a study of psoriatic arthritis patients on GLP-1 therapy reported improvements in joint pain, lower disease activity, and lower CRP
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