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The study identified six clinical manifestations, namely: post-exertion malaise (PEM) (87%), fatigue (85%), brain fog (64%), dizziness (62%), GI (59%), and palpitations (57%), as the most prominent PASC symptoms

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FEBS Lett 2003

Zhang, A

and the endoplasmic reticulum (ER) apoptotic pathway, which consists of three apoptotic pathways activated by the UPR (IRE1, PERK, and ATF6 pathways) (38)