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Some adjust quickly

Its commonly stated that the upper arm is harder to self-inject

(c) abstract and author debates or editorials

Some clinical experts and recent Phase 3 reporting have also noted that weight loss in some participants has been substantial enough to raise questions about how much weight loss may be too much, particularly when these medications are used outside tightly controlled medical settings and without provider supervision

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To put this in perspective, to justify their current valuation, they only have to grow their topline by ~7% for eight years while the overall obesity care market is expected to grow by ~26% CAGR