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Across STEP 1 and 3 trials involving non-diabetic participants, semaglutide 2.4 mg exhibited average placebo-adjusted weight reductions of 12.4% and 10.3%, respectively, by week 68
Why it happens: Nausea is the most common side effect of GLP-1s, especially when first starting or after a dose increase
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In 2021 sales amounted to $289 million and cash flow went negative to the tune of $15 million
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