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These compact, bifunctional molecules are designed to hijack the autophagy-lysosome pathway by conjugating a target-binding warhead to a lysosomotropic trigger

In addition, oral glutathione supplements have been linked to digestive distress, including abdominal cramps or bloating

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The assembly/disassembly of the FeS-Trx1 dimer fine tunes the activity of IRP1, a main regulator of iron homeostasis acting on the posttranslational level [13-15]

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Linkermann 32 and crossed with Parp1 / mice received from F