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Crucially, besides inducing membrane depolarization through 7nAChR-gated Ca2+ conductance, there is growing evidence suggesting potential metabotropic activities of this ionotropic receptor [43]

Step both compounds up slowly over the next 16 weeks to reach maintenance

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Devanaboyina M, Kaur J, Whiteley E, Lin L, Einloth K, Morand S, et al