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The GLP-1 drug mediated suppression of brain inflammation may turn out to be yet another key use case

Supresa Saffron Extract: Helps Manage Hunger, Appetite, and Sugar Cravings This patented, clinically-studied ingredient has been shown to reduce hunger, appetite, and sugar cravings.* Supresa is an extract of the stigmas from the Crocus sativus L

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because the peptides are fragile and can be damaged by improper handling, and because the additional preparation step provides an additional opportunity for bacterial contamination (Sigma Aldrich handling guide)

Grieco M, et al

These drugs imitate of the natural hormone and have been shown to significantly reduce weight and improve metabolic health