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its K311-site lactylation exacerbates cardiac injury by disrupting mitochondrial function and kynurenine metabolism, which may also contribute to hypertrophic remodeling (34)

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Access this article Similar content being viewed by others Abbreviations -MSH: -Melanozyten-stimulierendes Hormon DAG: Deutsche Adipositas-Gesellschaft GIP: Glukoseabhngiges insulinotropes Polypeptid GIPR: Rezeptor des glukoseabhngigen insulinotropen Polypeptids GLP-1: Glukagonhnliches Peptid 1 HbA 1c : Hmoglobin A 1c HOMA-IR: Homeostatic Model Assessment for Insulin Resistance HWZ: Halbwertszeit MC4R: Melanokortin-4-Rezeptor POMC: Proopiomelanokortin T2DM: Diabetes mellitus Typ 2 WHO: Weltgesundheitsorganisation Literatur Brandt SJ, Kleinert M, Tschop MH et al (2018) Are peptide conjugates the golden therapy against obesity

Avoid in pregnant or breastfeeding individuals due to a lack of appropriate data

As part of medical treatment, the patient receives an injection of a glutathione-containing solution

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