In: Verhoeckx K, Cotter P, Lpez-Esposito I, et al
Even if you dont feel thirsty, its extremely important to prioritize hydration when on these medications
The medication slows down gastric emptying, so it can lead to constipation, which gets worse without adequate hydration
Fractography of human intact long bone by bending
The primary mechanism of action involves stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, slowing gastric emptying, and promoting satiety through central nervous system pathways
Source: GLP-1.Reviews editorial walkthrough on April 13, 2026