Loperamide (Imodium) works for acute episodes but should not become a daily dependency
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This is the most common complaint in patient surveys about GLP-1 access (Luo et al., JAMA Network Open 2024)
implications for threshold and meaningful change estimation Helen Doll 1 , Michael DeRosa 2 , Shruti Dave 2 , Alyssa Bamer 3 1 Clinical Outcomes Solutions, Folkestone, UK, 2 Clinical Outcomes Solutions, Chicago, Illinois, USA, 3 Clinical Outcomes Solutions, Tucson, Arizona, USA Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :301.5 Aims Receiver operating characteristic (ROC) curve analysis is often used to estimate thresholds related to meaningful change or condition severity
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The provider injects corticosteroid into the knee joint and administers Toradol into the deltoid muscle