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Tissue sections were immunostained for TGF, p-Smad2, pSmad3, type I collagen and type II collagen and then assessed by immunofluorescence

Of 544 screened papers, the reviewers identified 36 studies meeting inclusion criteria 35 preclinical and one human study

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It is derived from a protein in the stomach and is purported to help healing of various tissues, including muscles, tendons, ligaments, cartilage, and even the gut