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Pancreatic Side Effects GLP-1 receptors are found not only in pancreatic islet cells but also in the exocrine duct cells of the pancreas [122]
Key Takeaways One of the largest clinical trials evaluating the role of semaglutide in weight management for adults showed that this medication can result in an average of 15% weight reduction from initial body weight over 68 weeks
Clinical trials show semaglutide reduces systolic blood pressure by around 3.5-5 mmHg compared to placebo, likely due to weight loss and direct metabolic effects
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