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Proteomics 19 (18), e1800311

Summary of mechanisms RIRI is a complex pathological process involving multiple intertwined factors and synergistic pathways, primarily including oxidative stress, inflammatory response, cell death, and microcirculatory dysfunction

The late development and maturation are related to the late cortical gliogenesis and convert brain cortical function from being purely neuronal to becoming neuronal-astrocytic

GHK-Cu also enhances the activation of metalloproteinases (MMPs) involved in breaking down damaged tissue and promoting new tissue formation

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One participant took DMSA and collected a urine sample, but did not send it to the lab due to lack of interest/time