The goal isn't rapid weight loss
31 On the other hand, knock down of the GLP-1producing neurons as well as chronic administration of the GLP-1 receptor antagonist (GLP-1 RA), exendin 939, was associated with hyperphagia and increased fat accumulation after high fat feeding in rats
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relevance to humans remains uncertain) The delayed gastric emptying caused by GLP-1 medications may affect the absorption of some oral medicines
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Switching is sometimes done when a patient has plateaued on one drug, when access or coverage changes, or when GI side effects require an alternative