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Several observations from this system strongly support a contact-dependent mechanism

[10] [11] [12] In the TMD domain a fulcrum of polar residues regulates the biased signaling of the receptor [10] while the transmembrane helical boundaries [13] and extracellular surface are a trigger for biased agonism

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Copper is an essential cofactor for dozens of enzymes, including lysyl oxidase (critical for collagen cross-linking) and superoxide dismutase (an antioxidant enzyme)

BMI: Body Mass Index

To obtain a reasonably good capacity reading, manufacturers commonly rate alkaline and lead acid batteries at a very low 0.05C, or a 20-hour discharge