Painless but rapid change in eyesight
Oral semaglutide Oral semaglutide, marketed as Rybelsus, was the first oral GLP-1 receptor agonist
These changes carry not only aesthetic implications but also functional concerns
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Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease
Less urgent but still worth reporting: side effects that do not improve after seven days at any dose level, persistent diarrhea that interferes with daily activities, significant hair thinning (which can occur during rapid weight loss phases and may relate to nutritional deficiencies rather than medication directly), mood changes including increased anxiety or depression, and hair loss patterns that seem disproportionate to weight loss speed