For years, much of the clinical benefit of GLP-1 receptor agonists in MASH has been attributed primarily to weight loss
This action slows the rate at which your stomach empties food into the small intestine, creating a prolonged feeling of fullness
Those with known nutrient deficiencies (which COVID can worsen), people experiencing dehydration from fever or gastrointestinal symptoms, and individuals who have trouble with oral supplements due to digestive issues also tend to see significant benefits
This is a natural reaction and nothing a cold compress cant fix
In a Phase 2 clinical trial published in the New England Journal of Medicine (Jastreboff et al., 2023), participants using retatrutide experienced up to 24% reduction in body weight over 48 weeks, significantly outperforming earlier GLP-1 agents
It works by mimicking a hormone called GLP-1 (glucagon-like peptide-1) that is naturally produced in the intestines